Auditory brainstem recordings.

<p>A–C) Auditory brainstem responses (ABR) at 8 kHz, 16 kHz and 32 kHz were made on <i>Slc26a7^+/+, Slc26a7^Δ/+</i> and <i>Slc26a7^Δ/Δ</i> mice at ages P22 through P100. There were no differences in auditory threshold between either <i>Slc26a7^Δ/Δ</i> or <i>Slc26a7^Δ/+</i> and <i>Slc26a7^+/+</i> mice during their early adult life. The auditory thresholds were unchanged among the genotypes. The numbers of animals for each mean threshold at P22, P56 and P100 are +/+: 11, 4, 7; <i>Δ/+</i>: 16, 13, 14; <i>Δ/Δ</i>: 10, 13, 12. D) The ABR of <i>Slc26a7^+/+, Slc26a7^Δ/+</i> and <i>Slc26a7^Δ/Δ</i> mice was measured before and after exposure to noise that produced a temporary auditory threshold shift. E) The ABR of <i>Slc26a7^+/+, Slc26a7^Δ/+</i> and <i>Slc26a7^Δ/Δ</i> mice was measured before and after exposure to noise that produced a permanent auditory threshold shift. The magnitude of the threshold shifts was not affected by the level of expression of <i>Slc26a7</i>. Numbers of animals are given by each bar.