<p><i>Wt</i> = wild type mice; M8 = <i>Mct8KO</i>; L2 = <i>Lat2KO</i>; M8L2 = <i>Mct8Lat2KO</i>. Measurements were by qPCR, and the data expressed relative to 18S RNA. Significance of differences was calculated by one way ANOVA and the Tukey posthoc test. Only relevant significant comparisons are indicated. * P<0.05. ** P<0.01. *** P<0.001. <i>Hr</i>: Hairless mRNA. <i>Sema7a</i>: Semaphorin 7a mRNA. <i>Klf9</i>: Kruppel factor 9, or BTEB mRNA. P0, P5, P15, P21: postnatal days 0, 5, 15, or 21.</p
<p>Figure shows mRNA data for FXR, SHP, and HNF4α in liver (L) and Fgf15 in ileum (I). Data are pres...
<p>Relative mRNA levels are normalized to WT controls. For normalization, the geometric means of <i>...
<p>The gene expression was determined by qRT-PCR as detailed in “<a href="http://www.plosone.org/art...
<p>(A) Western blot analysis. Compared to the 4- and 8-week-old mice, LRG protein levels were higher...
<p>(<b>A</b>) Levels in the kidney and whole brain of 18-month-old mice compared with 6-month-old mi...
<p><sup><i>a</i></sup>Each brain region was isolated from perfused postnatal day 21 mice as describe...
<p>A) Semi-quantitative Real-Time PCR revealed significantly higher <i>Aqp9</i> mRNA levels in the m...
<p><i>Wt</i> = wild type mice; M8 = <i>Mct8KO</i>. L2 = <i>Lat2KO</i>; M8L2 = <i>Mct8Lat2KO</i>...
<p>mRNA levels of various cytokines and chemokines (<b>A and B</b>) and metabolic genes (<b>C and D<...
<p>Selected autophagy markers analyzed by qRT-PCR in tissue from cerebral cortex from BACHD mice at ...
<p>A to C, Comparison of core clock genes in the liver (A), muscle (B), and kidney (C) between C57BL...
<p>(<b>A</b>) Heat map illustrating significant differences in global gene expression between BTBR T...
<p>Values are means ± SEM for A and B. (a) FASD mice (grey bar; 3 experiments combined; n = 10) had ...
<p>(A.1) Plot of the factor loadings from the exploratory factor analysis of the significantly diffe...
<p>(a) <i>Bmal1</i>, (b) <i>Per2</i>, (c) <i>Pfkfb3</i>, (d) <i>Pck</i>, (e) <i>Fbp1</i>, (f) <i>G6p...
<p>Figure shows mRNA data for FXR, SHP, and HNF4α in liver (L) and Fgf15 in ileum (I). Data are pres...
<p>Relative mRNA levels are normalized to WT controls. For normalization, the geometric means of <i>...
<p>The gene expression was determined by qRT-PCR as detailed in “<a href="http://www.plosone.org/art...
<p>(A) Western blot analysis. Compared to the 4- and 8-week-old mice, LRG protein levels were higher...
<p>(<b>A</b>) Levels in the kidney and whole brain of 18-month-old mice compared with 6-month-old mi...
<p><sup><i>a</i></sup>Each brain region was isolated from perfused postnatal day 21 mice as describe...
<p>A) Semi-quantitative Real-Time PCR revealed significantly higher <i>Aqp9</i> mRNA levels in the m...
<p><i>Wt</i> = wild type mice; M8 = <i>Mct8KO</i>. L2 = <i>Lat2KO</i>; M8L2 = <i>Mct8Lat2KO</i>...
<p>mRNA levels of various cytokines and chemokines (<b>A and B</b>) and metabolic genes (<b>C and D<...
<p>Selected autophagy markers analyzed by qRT-PCR in tissue from cerebral cortex from BACHD mice at ...
<p>A to C, Comparison of core clock genes in the liver (A), muscle (B), and kidney (C) between C57BL...
<p>(<b>A</b>) Heat map illustrating significant differences in global gene expression between BTBR T...
<p>Values are means ± SEM for A and B. (a) FASD mice (grey bar; 3 experiments combined; n = 10) had ...
<p>(A.1) Plot of the factor loadings from the exploratory factor analysis of the significantly diffe...
<p>(a) <i>Bmal1</i>, (b) <i>Per2</i>, (c) <i>Pfkfb3</i>, (d) <i>Pck</i>, (e) <i>Fbp1</i>, (f) <i>G6p...
<p>Figure shows mRNA data for FXR, SHP, and HNF4α in liver (L) and Fgf15 in ileum (I). Data are pres...
<p>Relative mRNA levels are normalized to WT controls. For normalization, the geometric means of <i>...
<p>The gene expression was determined by qRT-PCR as detailed in “<a href="http://www.plosone.org/art...