Phylogenetic trees of the α-/θ-defensin (<i>DEFA</i>/<i>DEFT</i>) genes in primates and treeshrews.

<p>A: Phylogenetic tree of primate and treeshrew <i>DEFA/DEFT</i> genes based only on the signal-prosegment region. The BI tree is selected as the background tree. The major clades or clusters having similar topologies from all three tree-building methods (BI, NJ and ML) are combined and labeled with the BI posterior probabilities and the bootstrap support values from the NJ and ML analyses. Primate <i>DEFA/DEFT</i> genes are clustered into prosimian and simian clades. The simian clades are classified and named following the nomenclature used for the human <i>DEFA/DEFT</i> genes. The “P” in node labels denotes a pseudogene, and the “U” indicates a gene with an ambiguous locus from the species in the synteny map in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0097425#pone-0097425-g007" target="_blank">Figure 7</a>. B: Phylogenetic tree of primate and treeshrew <i>DEFA/DEFT</i> genes based the entire coding region. The BI tree is selected as the background tree. The treeshrew <i>DEFA</i> genes are the outgroups of the two separate clades.