<p>B6 or IL-17<sup>−/−</sup> mice were aerosol infected with ∼100 cfu <i>Mtb</i> H37Rv (a), <i>Mtb</i> HN878 (b) or <i>Mtb</i> CDC1551 (c). Lung bacterial burden was determined by plating on D30 or D60 post-infection. The data points represent the mean (±SD) of values from 3–5 samples. *p≤0.05, ***p≤0.0005, ns-not significant.</p
<p>C57BL/6 mice were challenged with H37Rv, BCG, H37RvΔRD1 or BCG::RD1 by the aerosol route and lung...
<p>WT or TLR4<sup>lps-d</sup>/TLR9<sup>−/−</sup> mice were challenged with 8×10<sup>2</sup> CFU <i>K...
<p>Animals were infected with the indicated bacterial strains for 30 days and treated with antibioti...
<p>B6 mice were either aerosol infected with ∼100 cfu <i>Mtb</i> H37Rv or <i>Mtb</i> HN878. Lungs we...
<p>Hematopoietic IL-17R<sup>−/−</sup> BMC mice (B6 host/−/− BM), non-hematopoietic IL-17R<sup>−/−</s...
<p>1×10<sup>6</sup> lung DCs from B6 mice were infected in vitro with <i>Mtb</i> H37Rv or <i>Mtb</i>...
<p>B6 and IL-17<sup>−/−</sup> mice were aerosol infected with ∼100 cfu <i>Mtb</i> HN878 and lungs we...
<p>C57BL/6 mice (black bars) and IL-22<sup>−/−</sup> (white bars) mice were infected with approx. 10...
<p>. Wild-type (BALB/c), IL-4Rα<sup>-/-</sup> and IL-4Rα macrophage cell-specific deficient mice (Ly...
<p>C57BL/6 (filled circles) and AID<sup>−/−</sup>µS<sup>−/−</sup> mice (opened circles) were infecte...
Nontuberculous mycobacteria (NTM) infection is common in patients with structural lung damage. To ad...
<p>Bacterial burden in the lungs following aerosol infection with Mtb at doses of 100 CFU (A), 150 C...
<p>B6 and CXCR5<sup>−/−</sup> mice were aerosol infected with ∼100 cfu <i>Mtb</i> HN878 and lung bac...
<p>(A) C57BL/6 mice were infected with individual KZN strains by aerosol. CFU of homogenates of lung...
<p>Single cell suspensions from lungs of WT and TLR2KO mice were re-stimulated overnight with Mtb-pu...
<p>C57BL/6 mice were challenged with H37Rv, BCG, H37RvΔRD1 or BCG::RD1 by the aerosol route and lung...
<p>WT or TLR4<sup>lps-d</sup>/TLR9<sup>−/−</sup> mice were challenged with 8×10<sup>2</sup> CFU <i>K...
<p>Animals were infected with the indicated bacterial strains for 30 days and treated with antibioti...
<p>B6 mice were either aerosol infected with ∼100 cfu <i>Mtb</i> H37Rv or <i>Mtb</i> HN878. Lungs we...
<p>Hematopoietic IL-17R<sup>−/−</sup> BMC mice (B6 host/−/− BM), non-hematopoietic IL-17R<sup>−/−</s...
<p>1×10<sup>6</sup> lung DCs from B6 mice were infected in vitro with <i>Mtb</i> H37Rv or <i>Mtb</i>...
<p>B6 and IL-17<sup>−/−</sup> mice were aerosol infected with ∼100 cfu <i>Mtb</i> HN878 and lungs we...
<p>C57BL/6 mice (black bars) and IL-22<sup>−/−</sup> (white bars) mice were infected with approx. 10...
<p>. Wild-type (BALB/c), IL-4Rα<sup>-/-</sup> and IL-4Rα macrophage cell-specific deficient mice (Ly...
<p>C57BL/6 (filled circles) and AID<sup>−/−</sup>µS<sup>−/−</sup> mice (opened circles) were infecte...
Nontuberculous mycobacteria (NTM) infection is common in patients with structural lung damage. To ad...
<p>Bacterial burden in the lungs following aerosol infection with Mtb at doses of 100 CFU (A), 150 C...
<p>B6 and CXCR5<sup>−/−</sup> mice were aerosol infected with ∼100 cfu <i>Mtb</i> HN878 and lung bac...
<p>(A) C57BL/6 mice were infected with individual KZN strains by aerosol. CFU of homogenates of lung...
<p>Single cell suspensions from lungs of WT and TLR2KO mice were re-stimulated overnight with Mtb-pu...
<p>C57BL/6 mice were challenged with H37Rv, BCG, H37RvΔRD1 or BCG::RD1 by the aerosol route and lung...
<p>WT or TLR4<sup>lps-d</sup>/TLR9<sup>−/−</sup> mice were challenged with 8×10<sup>2</sup> CFU <i>K...
<p>Animals were infected with the indicated bacterial strains for 30 days and treated with antibioti...