<i>In-vivo</i> set point control experiment on IRMA.

<p>(Top panel) the desired ( in blue) and experimentally quantified GFP ( in green) are shown for the whole duration of the experiment; the control action starts at time and lasts for . The p-value estimates the statistical significance of the control action in maintaining the desired set-point (Supplementary Material). (Bottom panel) the input signal computed by the control algorithm is shown in red. (Insets) Images taken during the experiment show the growing yeast population at the beginning, at the half and at the end of the experiment.