<p>The three FHA domains, Rad53-FHA1, Dun1-FHA and Ki67-FHA, are shown in (a), (b) and (c), respectively. We extracted the residues of 6 loops. The columns separated by red lines represent 6 loops of each FHA domain. For example, loops 1 to 6 is shown from the left to right column (see blue letters). Red letters are the conserved residues. The darker color means the two residues have stronger correlated movements (Black indicates strong correlations and white weak correlations.).</p
Correlated mutation analysis is an effective approach for predicting functional and structural resid...
<p>The color scale is represented on the right ranging from red to blue: highly positive correlation...
<p>(A) Combined contact plots for the head domain and part of the rod domain showing the probability...
<p>The fold of the FHA domain includes 11 β sheets linked by loops. The loops that connect different...
<p>FHA domains contain five conserved residues, Gly (a) and (b), His (c), Arg (d), Ser (e) and Asn (...
<p>Sequence logos of HTH DNA-binding domains and corresponding binding sites are shown on the top an...
<p>(a) Sequence alignment of the FHA domain from different proteins. The β strands and loops are in ...
<p>Cartoon representation of <i>A</i>, murine mAb 18B7 V<sub>H</sub>-C<sub>H1</sub> and <i>B</i>, ch...
Highly correlated, spatially distant regions are sites for possible allosteric modification. Such pa...
<p>We summarize the key domain–peptide interactions of Rad53-FHA1 (a), Dun1-FHA (b) and Ki67-FHA (c)...
a window size of 7. Red highlighting on the alignment shows the known locations of interactions with...
<p>“Contact” map of significant inter-residue correlations. Significant (p≤0.025) WT NBD1 correlatio...
<p>(<b>A</b>) Distribution of the cross-correlation values for 20 protein domain pairs. A higher num...
<p>The color coding red represents the positive correlation, green as negative correlation. The blac...
<p><b>(A</b>) Phosphoribosylanthranilate isomerase, (<b>B</b>) cyclophilin, (<b>C</b>) sialidase and...
Correlated mutation analysis is an effective approach for predicting functional and structural resid...
<p>The color scale is represented on the right ranging from red to blue: highly positive correlation...
<p>(A) Combined contact plots for the head domain and part of the rod domain showing the probability...
<p>The fold of the FHA domain includes 11 β sheets linked by loops. The loops that connect different...
<p>FHA domains contain five conserved residues, Gly (a) and (b), His (c), Arg (d), Ser (e) and Asn (...
<p>Sequence logos of HTH DNA-binding domains and corresponding binding sites are shown on the top an...
<p>(a) Sequence alignment of the FHA domain from different proteins. The β strands and loops are in ...
<p>Cartoon representation of <i>A</i>, murine mAb 18B7 V<sub>H</sub>-C<sub>H1</sub> and <i>B</i>, ch...
Highly correlated, spatially distant regions are sites for possible allosteric modification. Such pa...
<p>We summarize the key domain–peptide interactions of Rad53-FHA1 (a), Dun1-FHA (b) and Ki67-FHA (c)...
a window size of 7. Red highlighting on the alignment shows the known locations of interactions with...
<p>“Contact” map of significant inter-residue correlations. Significant (p≤0.025) WT NBD1 correlatio...
<p>(<b>A</b>) Distribution of the cross-correlation values for 20 protein domain pairs. A higher num...
<p>The color coding red represents the positive correlation, green as negative correlation. The blac...
<p><b>(A</b>) Phosphoribosylanthranilate isomerase, (<b>B</b>) cyclophilin, (<b>C</b>) sialidase and...
Correlated mutation analysis is an effective approach for predicting functional and structural resid...
<p>The color scale is represented on the right ranging from red to blue: highly positive correlation...
<p>(A) Combined contact plots for the head domain and part of the rod domain showing the probability...