a window size of 7. Red highlighting on the alignment shows the known locations of interactions with other domains. See text for details.<p><b>Copyright information:</b></p><p>Taken from "The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction"</p><p>http://www.biomedcentral.com/1471-2105/9/51</p><p>BMC Bioinformatics 2008;9():51-51.</p><p>Published online 25 Jan 2008</p><p>PMCID:PMC2267696.</p><p></p
Motivation: Compensating alterations during the evolution of protein families give rise to coevolvin...
A protein's function depends on functional residues that determine its binding specificity or its ca...
Motivation: The underlying assumption of many sequence-based comparative studies in proteomics is th...
Background: Amino acids responsible for structure, core function or specificity may be inferred from...
<p>(<b>A</b>) Average fractions of non-synonymous mutations in residues determined by the various re...
Conserved domains carry many of the functional features found in the proteins of an organism. This i...
<p>The alignment comprising reference sequences for each of the subfamilies was color coded to show ...
Correlated mutation analysis is an effective approach for predicting functional and structural resid...
Residue-residue interactions that fold a protein into a unique three-dimensional structure and make ...
<div><p>Residue-residue interactions that fold a protein into a unique three-dimensional structure a...
Background: The functional sites of a protein present important information for determining its cell...
Residue-residue interactions that fold a protein into a unique three-dimensional structure and make ...
BACKGROUND: The functional sites of a protein present important information for determining its cell...
Many proteins have evolved to form specific molecular complexes and the specificity of this interact...
Proteins are flexible, and this flexibility has an essential functional role. Flexibility can be obs...
Motivation: Compensating alterations during the evolution of protein families give rise to coevolvin...
A protein's function depends on functional residues that determine its binding specificity or its ca...
Motivation: The underlying assumption of many sequence-based comparative studies in proteomics is th...
Background: Amino acids responsible for structure, core function or specificity may be inferred from...
<p>(<b>A</b>) Average fractions of non-synonymous mutations in residues determined by the various re...
Conserved domains carry many of the functional features found in the proteins of an organism. This i...
<p>The alignment comprising reference sequences for each of the subfamilies was color coded to show ...
Correlated mutation analysis is an effective approach for predicting functional and structural resid...
Residue-residue interactions that fold a protein into a unique three-dimensional structure and make ...
<div><p>Residue-residue interactions that fold a protein into a unique three-dimensional structure a...
Background: The functional sites of a protein present important information for determining its cell...
Residue-residue interactions that fold a protein into a unique three-dimensional structure and make ...
BACKGROUND: The functional sites of a protein present important information for determining its cell...
Many proteins have evolved to form specific molecular complexes and the specificity of this interact...
Proteins are flexible, and this flexibility has an essential functional role. Flexibility can be obs...
Motivation: Compensating alterations during the evolution of protein families give rise to coevolvin...
A protein's function depends on functional residues that determine its binding specificity or its ca...
Motivation: The underlying assumption of many sequence-based comparative studies in proteomics is th...