<p>All experiences were performed at least 2 times.</p><p>Statistical <i>P</i> value compared to <i>AppΔapxIΔapxIIC</i> untreated cells: <i>P</i> = 0.15.</p><p>Statistically significative compared to <i>AppΔapxIΔapxIIC</i> untreated cells: *<i>P</i><0.05, **<i>P</i><0.01, ***<i>P</i><0.001.</p><p>Statistically significative compared to other viruses: <i><sup>a</sup>P</i><0.01.</p
Because many aspects of viral infection dynamics and inhibition are governed by stochastic processes...
<p>(<b>A</b>) A549 cells were transfected with 10 ng/ml 5′pppRNA 24 h prior to infection with VSVΔ51...
<p>IC<sub>50</sub> measured in a cell-based CPE assay (µM) with triplicate data points for VEEV 3526...
<p>Detection of the N viral protein in PRRSV infected SJPL cells by immunofluorescence. SJPL cells w...
(A) A549 cells were pre-treated with 3 μM of small molecules or an equivalent amount of DMSO for 2 h...
<p>Data are mean values ± SD from at least three independent experiments. The cytotoxicity values (C...
<p>qRT-PCR results expressed in relative expression (ΔΔCT) for IFNα (A), IFNβ (B) and IFNγ (C) in SJ...
<p>Shown are mean values calculated from at least three experiments ± SD. The cytotoxicity values (C...
(A & B) For determination of virus replication, A549 cells were pre-treated with small molecules at ...
<p>(A) Western blot analysis for the expression of ZAP in A549 cells transduced with lentiviruses ca...
<p>(A–D) Cells were treated for 30 minutes with DMSO (volume-matched) or 5 µM of WP1130 or its deriv...
<p>For the viral replication assay, STSA-1 cells grown in 24-well plates were infected with either G...
<p><sup>a</sup> IC<sub>50</sub> values were calculated in comparison to untreated infected cells. Ea...
<p>Antiviral activity in the supernatant of poly:IC-transfected cells, mock-infected cells and HAstV...
<p>SulCOS1 cells were transfected with efficient small interfering RNA (siRNA) against AIF (AIF1) or...
Because many aspects of viral infection dynamics and inhibition are governed by stochastic processes...
<p>(<b>A</b>) A549 cells were transfected with 10 ng/ml 5′pppRNA 24 h prior to infection with VSVΔ51...
<p>IC<sub>50</sub> measured in a cell-based CPE assay (µM) with triplicate data points for VEEV 3526...
<p>Detection of the N viral protein in PRRSV infected SJPL cells by immunofluorescence. SJPL cells w...
(A) A549 cells were pre-treated with 3 μM of small molecules or an equivalent amount of DMSO for 2 h...
<p>Data are mean values ± SD from at least three independent experiments. The cytotoxicity values (C...
<p>qRT-PCR results expressed in relative expression (ΔΔCT) for IFNα (A), IFNβ (B) and IFNγ (C) in SJ...
<p>Shown are mean values calculated from at least three experiments ± SD. The cytotoxicity values (C...
(A & B) For determination of virus replication, A549 cells were pre-treated with small molecules at ...
<p>(A) Western blot analysis for the expression of ZAP in A549 cells transduced with lentiviruses ca...
<p>(A–D) Cells were treated for 30 minutes with DMSO (volume-matched) or 5 µM of WP1130 or its deriv...
<p>For the viral replication assay, STSA-1 cells grown in 24-well plates were infected with either G...
<p><sup>a</sup> IC<sub>50</sub> values were calculated in comparison to untreated infected cells. Ea...
<p>Antiviral activity in the supernatant of poly:IC-transfected cells, mock-infected cells and HAstV...
<p>SulCOS1 cells were transfected with efficient small interfering RNA (siRNA) against AIF (AIF1) or...
Because many aspects of viral infection dynamics and inhibition are governed by stochastic processes...
<p>(<b>A</b>) A549 cells were transfected with 10 ng/ml 5′pppRNA 24 h prior to infection with VSVΔ51...
<p>IC<sub>50</sub> measured in a cell-based CPE assay (µM) with triplicate data points for VEEV 3526...