Modeling free β-arrestin 2 and free (unbound to β-arrestin 2) cell surface receptors over time.

<p>(A) Model output of the % of initial free β-arrestin 2 through 40 min in CXCR4⁺, CXCR7⁺, or CXCR4⁺-CXCR7⁺ cells treated with 1000 ng/mL CXCL12-α. (B) Model output of % of initial free (unbound to β-arrestin 2) cell surface receptors through 40 min in cells treated with 1000 ng/mL CXCL12. Legend denotes the specific receptor and cell type on which the receptor is expressed.