Association between unfavourable outcomes and strain type in multivariate analyses.

<p>REA = Restriction endonuclease analysis. PCR = Polymerase chain reaction. MLVA = Multiple-Locus Variable number tandem repeat Analysis. STRD = Summed Tandem-Repeat Difference. MLST = Multilocus Sequence Typing. NR = not reported;</p><p><b>^*</b>Overall % of strain BI in the cohort, the % in the sub-population used for multivariate analyses was not reported.^** % of binary toxin gene and <i>tcd</i>C mutation respectively, the % of combinations were not reported.</p>a<p>Comparison of clade 2 with 99% PCR ribotype 027 vs. clade 1, and clade 5 with 100% PCR ribotype 078 vs. clade 1.^b Compared to infrequent ribotypes in the study (other than R01, 02, 05, 015, 016, 023, 027, 064, 078 and 106).^c Hypervirulent strain vs. non-hypervirulent, ribotype 027 was prevailing during the study period.^d Other ribotype: non-027 and non-017.