Respective abilities of mutant β clamp proteins to support DNA damage-induced mutagenesis.

<p>Frequencies of (<b>A</b>) UV- or (<b>B</b>) MMS-induced mutagenesis were measured as described in <i>Material and Methods</i> using strains RW118 (WT; <i>dnaN⁺ umuD⁺C⁺</i>), RW120 (ΔumuD; <i>dnaN⁺</i> Δ<i>umuDC595</i>::<i>cat</i>), or the <i>umuD⁺C⁺</i> plasmid shuffle strains MS202 (β⁺), MS203 (β^Q61K), MS204 (β^S107L), MS205 (β^G157S), MS206 (β^V170M), MS207 (β^E202K) and MS208 (β^M204K), as indicated. Results represent the average of 5 independent determinations. Error bars represent one standard deviation. <i>P</i>-values ≤0.05 are indicated, and were calculated using the Student's <i>t</i>-test.