<p>Frequencies of <b>(A)</b> MMS-induced (2 mM) and <b>(B)</b> UV-induced mutagenesis (60 J/m<sup>2</sup>) were measured as described in <i>Materials and Methods</i>. Results represent the average of 3 independent determinations using 2 independent clones for each <i>dnaN</i> allele ± one standard deviation. Bars are color coded to indicate mutations analyzed map to loop I (red), loop II (blue) or the central pore (green) of the β clamp. Symbols: *, <i>p</i> < 0.05; **, <i>p</i> < 0.001.</p
<p>(A) Effect of mutations impairing DNA polymerases on HC formation. Results of 3 to 14 experiments...
Mutagenic DNA repair (MDR) transiently increases mutation rate through the activation of low-fidelit...
International audienceUltraviolet radiation induces a wide variety of damage in DNA that can origina...
<p>Frequencies of (<b>A</b>) UV- or (<b>B</b>) MMS-induced mutagenesis were measured as described in...
<p>DNA damage-induced mutation frequencies following exposure of MutS-deficient <i>dinB<sup>+</sup><...
<p><b>(A)</b> The dependence of MMS-induced mutagenesis on Pol IV (<i>dinB</i>) and Pol V (<i>umuDC<...
A study of the alteration of the DNA in the mutant gene can determine mechanisms of mutation by dist...
<p>H<sub>2</sub>O<sub>2</sub>-induced mutagenesis was measured in <i>mutS<sup>+</sup></i> (<b>A</b>)...
DNA alterations induced in V79 cells treated with UV light or methyl-nitro-nitrosoguanidine were ana...
We describe how mutant yield data (mutants per cell treated) can be used both to compare the mutagen...
<p>(A) FAM fluorescent signals and (B) corresponding standard curve generated from plasmid standard ...
The elucidation of many biological and meta-bolic processes has been facilitated by the use of micro...
<p>(<b>A</b>) Genomic structure of the <i>dnaA-dnaN-recF</i> operon. Genes in grey are essential for...
<p>Percent survival was plotted as a function of UV dose for strains expressing the β strand I<sub>1...
<p>(A) Enrichment of GFP<sup>+</sup> cells after hygromycin selection. Scale bar = 50 µm. (B) ZFN-dr...
<p>(A) Effect of mutations impairing DNA polymerases on HC formation. Results of 3 to 14 experiments...
Mutagenic DNA repair (MDR) transiently increases mutation rate through the activation of low-fidelit...
International audienceUltraviolet radiation induces a wide variety of damage in DNA that can origina...
<p>Frequencies of (<b>A</b>) UV- or (<b>B</b>) MMS-induced mutagenesis were measured as described in...
<p>DNA damage-induced mutation frequencies following exposure of MutS-deficient <i>dinB<sup>+</sup><...
<p><b>(A)</b> The dependence of MMS-induced mutagenesis on Pol IV (<i>dinB</i>) and Pol V (<i>umuDC<...
A study of the alteration of the DNA in the mutant gene can determine mechanisms of mutation by dist...
<p>H<sub>2</sub>O<sub>2</sub>-induced mutagenesis was measured in <i>mutS<sup>+</sup></i> (<b>A</b>)...
DNA alterations induced in V79 cells treated with UV light or methyl-nitro-nitrosoguanidine were ana...
We describe how mutant yield data (mutants per cell treated) can be used both to compare the mutagen...
<p>(A) FAM fluorescent signals and (B) corresponding standard curve generated from plasmid standard ...
The elucidation of many biological and meta-bolic processes has been facilitated by the use of micro...
<p>(<b>A</b>) Genomic structure of the <i>dnaA-dnaN-recF</i> operon. Genes in grey are essential for...
<p>Percent survival was plotted as a function of UV dose for strains expressing the β strand I<sub>1...
<p>(A) Enrichment of GFP<sup>+</sup> cells after hygromycin selection. Scale bar = 50 µm. (B) ZFN-dr...
<p>(A) Effect of mutations impairing DNA polymerases on HC formation. Results of 3 to 14 experiments...
Mutagenic DNA repair (MDR) transiently increases mutation rate through the activation of low-fidelit...
International audienceUltraviolet radiation induces a wide variety of damage in DNA that can origina...