<p>Frozen PBMCs samples taken from male rhesus macaque 12 weeks after the MVA boost (Week 20 sample) were thawed and restimulated for 16 hours with TRAP peptides prior staining for IFN-γ production and memory/effector T cell markers. a.) Graphs represent the frequency of IFN-γ<sup>+</sup> CD4<sup>+</sup> T cells (left panel), frequency of T cell subset<sup>+</sup> CD4<sup>+</sup> T cells (central panel) or the frequency of each T cell subsets as a percentage of IFN-γ<sup>+</sup> CD4<sup>+</sup> T cells (right panel). b.) Graphs represent the frequency of IFN-γ<sup>+</sup> CD8<sup>+</sup> T cells (left panel), frequency of T cell subset<sup>+</sup> CD8<sup>+</sup> T cells (central panel) or the frequency of each T cell subsets as a percentag...
<p>Memory subsets were defined on differential expression of CCR7 and CD28 within the CD95<sup>+</su...
<p>Rhesus macaques were immunized intramuscularly with F4/AS01 (‘P’) and/or AdC7-GRN (‘A’), accordin...
<p>Plot overlays show the phenotypic and functional characterization of the CE-specific T cells indu...
<p>Male rhesus macaque were vaccinated i.m. with either ChAd63.ME-TRAP followed 8 weeks later by MVA...
<p>PBMCs were collected from immunized macaques at 10 months following a fourth immunization to eval...
<p>Cryopreserved rhesus macaque PBMCs were thawed, phenotyped and assessed for function. (A) Graphs ...
<p>T-cell responses of PBMCs from immunized Rhesus macaques to 12 pools, each consisting of ten gag ...
<p>Male rhesus macaques were immunised i.m. with 10<sup>8</sup>iu ChAd63.ME-TRAP alone or mixed toge...
<p>(<b>A</b>) Overview of primate experimental design. Three primates were immunized thrice with MVA...
<p>Intracellular cytokine staining was performed on BALF collected from both vaccine groups at 4 wee...
<p>Comparison of the average number of IFN-γ<sup>+</sup> cells activated by Gag 15- and 20-aa peptid...
<p>Male rhesus macaques were immunized i.d. at weeks 0 and 6 with either 10<sup>8</sup> PFU MVA-Ag85...
<p>(A) Number of CD4<sup>+</sup> T cells, and (B) the percentage of CD4<sup>+</sup> CD95<sup>+</sup>...
<p>(<b>A</b>) Vaccination schedule of the animals primed with p24CE DNA (Vaccination 1 and 2) and bo...
<p>IFN-γ ELISPOT assays were performed with PBMC samples from each of five Rhesus macaques immunized...
<p>Memory subsets were defined on differential expression of CCR7 and CD28 within the CD95<sup>+</su...
<p>Rhesus macaques were immunized intramuscularly with F4/AS01 (‘P’) and/or AdC7-GRN (‘A’), accordin...
<p>Plot overlays show the phenotypic and functional characterization of the CE-specific T cells indu...
<p>Male rhesus macaque were vaccinated i.m. with either ChAd63.ME-TRAP followed 8 weeks later by MVA...
<p>PBMCs were collected from immunized macaques at 10 months following a fourth immunization to eval...
<p>Cryopreserved rhesus macaque PBMCs were thawed, phenotyped and assessed for function. (A) Graphs ...
<p>T-cell responses of PBMCs from immunized Rhesus macaques to 12 pools, each consisting of ten gag ...
<p>Male rhesus macaques were immunised i.m. with 10<sup>8</sup>iu ChAd63.ME-TRAP alone or mixed toge...
<p>(<b>A</b>) Overview of primate experimental design. Three primates were immunized thrice with MVA...
<p>Intracellular cytokine staining was performed on BALF collected from both vaccine groups at 4 wee...
<p>Comparison of the average number of IFN-γ<sup>+</sup> cells activated by Gag 15- and 20-aa peptid...
<p>Male rhesus macaques were immunized i.d. at weeks 0 and 6 with either 10<sup>8</sup> PFU MVA-Ag85...
<p>(A) Number of CD4<sup>+</sup> T cells, and (B) the percentage of CD4<sup>+</sup> CD95<sup>+</sup>...
<p>(<b>A</b>) Vaccination schedule of the animals primed with p24CE DNA (Vaccination 1 and 2) and bo...
<p>IFN-γ ELISPOT assays were performed with PBMC samples from each of five Rhesus macaques immunized...
<p>Memory subsets were defined on differential expression of CCR7 and CD28 within the CD95<sup>+</su...
<p>Rhesus macaques were immunized intramuscularly with F4/AS01 (‘P’) and/or AdC7-GRN (‘A’), accordin...
<p>Plot overlays show the phenotypic and functional characterization of the CE-specific T cells indu...