Ontology of genes differentially expressed at 7 h and 24 h of incubation after 2 h of OGD.

<p>Gene ontology analyses included genes that had a <i>p</i>-value <0.05 and a fold change of 2.0 and were performed using GoMiner. Classes were selected manually and the number of genes for each class divided by the sum of the total number of genes in the selected classes (586 genes at 7 h and 403 genes at 24 h). Note that some genes are included in more than one class. (<b>A</b>) Ontology of genes up-regulated (upper) and down-regulated (lower) relatively to the control at 7 h of incubation in culture conditioned medium after 2 h OGD. In this analysis, the total numbers of up-regulated and down-regulated genes were 232 and 354, respectively. (<b>B</b>) Ontology of genes up-regulated (upper) and down-regulated (lower) relatively to the control at 24 h of incubation in culture conditioned medium after 2 h OGD. In this analysis, the total numbers of up-regulated and down-regulated genes were 333 and 70, respectively. (<b>C</b>) Ontology of genes up-regulated (upper) and down-regulated (lower) at 7 h and 24 h of incubation in culture conditioned medium after 2 h OGD. In this analysis, the total numbers of up-regulated and down-regulated genes were 60 and 31, respectively.