Detection of apoptotic cells and CD11b-positive cells in pancreatic tissue of B6-mtAKR and B6-mtFVB mice.

<p>Pancreatic sections of 3 and 12-month-old mice at the indicated time points after initiation of cerulein treatment (n = 5–6 per group) were stained with the ApopTag Kit for the detection of apoptotic cells (A, B), or processed applying the ABC technique and a CD11b-specific antibody (C). (A) Representative photographs of apoptotic cells (indicated by arrows) in the tissue of 12-month-old B6-mtFVB mice. (B, C) Positive-stained cells were counted, and mean values ± SEM were calculated. (B) *P_U<0.0166 vs. <u>0 h</u> with Bonferroni-adjusted α = 0.0166. (C) *P_U<0.001 vs. <u>0 h</u> each.