Validation of reduced miR-34b and miR-106b* levels in stage I lung adenocarcinoma and normal adjacent lung tissue.

<p>miR-34b and miR-106b* expression was measured using TaqMan qRT-PCR in a second cohort of stage I lung adenocarcinoma and adjacent normal lung tissue. ΔCt values graphed are relative to the endogenous small RNA control RNU48 with SEM. (A) Mean relative ΔCt value of tumors that did and did not relapse (n = 8) compared to mean value of adjacent normal lung tissues for both tumors (n = 7), *p = 0.03. (B) Mean relative ΔCt values of recurrent lung adenocarcinoma (n = 3) or adjacent normal lung tissue (n = 3), *p = 0.02. (C) Mean relative ΔCt values in tumors that did (n = 3) or did not (n = 5) relapse, *p = 0.02. (D) Mean relative ΔCt values of adjacent normal lung tissue from patients that did (n = 3) or did not relapse (n = 4), *p = 0.05. All p values calculated by student's t-test.