FA injection induces interstitial cell infiltration in transgenic line A homozygous mice.

<p>The inflammatory cell infiltration was characterized by immunohistochemistry with anti-F4/80 (monocytes/macrophages) and anti-CD3 (T cells) antibodies. (A and B). Representative immunostaining of one mouse from each group (x400 magnification). (C) Quantification of positive IHC signals were quantified for (a) F4/80, (b) CD3 and (c) PCNA using KS300 image analyzer software. All parameters were significantly increased in transgenic mice. Data are shown as the mean ± SEM of 14–18 mice per group * p < 0.05; ** p < 0.01 vs WT-FA.