Visualization and determination of vascular density using CD31 immunohistochemistry in virus-treated (LIVP 6.1.1 or GLV-5b451) and PBS-treated tumors at 28 dpvi.
- Marion Adelfinger (127233)
- Ivaylo Gentschev (7236)
- Julio Grimm de Guibert (610494)
- Stephanie Weibel (127241)
- Johanna Langbein-Laugwitz (282757)
- Barbara Härtl (132752)
- Hugo Murua Escobar (50025)
- Ingo Nolte (50031)
- Nanhai G. Chen (132760)
- Richard J. Aguilar (453124)
- Yong A. Yu (164649)
- Qian Zhang (49333)
- Alexa Frentzen (127246)
- Aladar A. Szalay (127251)
Publication date
August 2014
DOIAbstract
<p>(<b>A</b>) Tumor sections labeled with anti-CD31 antibody (red) and anti-vaccinia virus (VV) antibody (green). Scale bars: 150 µm. (<b>B, C</b>) The vascular density was measured in CD31-labeled tumor cross-sections (n = 3 mice per group, 16 images per mouse) and presented as mean values +/− SD. (***P<0.001, **P<0.01,*P<0.05 Student's t-test).</p
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