Morphometric and MRI analysis of HD mouse model hearts.

<p>(A) Heart weight to tibia length index (B) Comparison of the left ventricle end-diastolic volume (LVEDV), left ventricle end-systolic volume (LVESV), ejection fraction (EF) cardiac output (CO) and stroke volume (SV) between WT and <i>Hdh</i>Q150 mice at 22 months of age. There are significant differences in the LVEDV, LVESV, SV and CO. (C) End diastolic and systolic frames of a short axis myocardium slice for WT and <i>Hdh</i>Q150 mice. All values are mean ± SEM (<i>n</i> = 4/gender/genotype/age). Student's <i>t</i> test: *<i>p</i><0.05, **<i>p</i><0.01, ***<i>p</i><0.001.