Cardiac output and left ventricular dilation.

<p><b>A</b>, Fractional Shortening (FS), Ejection Fraction (EF) and (<b>B</b>) Left ventricular diameter in diastole (LVVD) measurements collected from 36 week old <i>smLrp1</i>^<i>+/+</i> and <i>smLrp1</i>^<i>-/-</i> mice. * <i>P</i><0.05 <b>C</b>, Left ventricular volumes during diastole were determined during the 22 week study period with echocardiograms at indicated intervals. *<i>P</i><0.01, versus aortic root diameter of eight week old <i>smLrp1</i>^<i>-/-</i> mice; †<i>P</i><0.05, pair wise comparison among age-matched <i>smLrp1</i>^<i>+/+</i> mice.