<p><b>A, B.</b> Blood serum from fasted mice at 12 weeks of age (more than 4 mice per group). IGF-1 circulating levels measured by ELISA in females (<b>A</b>) and males (<b>B</b>) comparing the four possible genotypes. Error bars represent 1×s.e.m. *P<0.05; **P<0.01. ns = non-significant.</p
<p>Similar blood glucose levels were observed with both groups of mice with levels higher in males t...
<p>Error bars represent SD for n = 3 mice in each group. Statistical significance is indicated by * ...
<p>Antigen-specific antibody responses at week 4 (IgG—A, IgG1—B and IgG2a—C) and HI titer (D) at wee...
<p>Longitudinal measurements of (A) blood glucose and (B) serum IGF-1 in CH/XPA versus XPA and WT co...
<p><b>A, B.</b> Body weights of at least 8 mice per genotype per sex and time point were scored. The...
<p>(A) KD-fed mice showed lower blood glucose than controls on day 7 (***p<0.001). Animals in the K...
<p>B: Expression of IGF-II precursor (23 kDa) in muscle tissues from 11-, 29- and 54-week female Fzt...
<p>Average IOP of male mice was not significantly different between the 3 genotypes (<i>p>0</i>.<i>0...
<p>A, STZ injection resulted in elevated blood glucose levels in mice. B, Diabetic mice had lower bo...
<p>Male mice have increased spleen (A) and brain (B) fungal burden during chronic infection and incr...
<p>Mice were vaccinated with indicated doses. Four weeks later mice were sacrificed, and serum and B...
<p>Mice fed with a high AGE diet (n = 5) or a regular AGE diet (n = 5) for 26 and 39 weeks were anal...
<p>Four month old animals were fasted for 4 hours prior to sample collection. Values are represented...
<p>Hyperinsulinemic euglycemic clamp studies were conducted to calculate (A) Ginf, (B) GDR, (C) HGO,...
<p>The lengths of tibiae (A) and femora (B) from 33 weeks old mice with the indicated genotypes were...
<p>Similar blood glucose levels were observed with both groups of mice with levels higher in males t...
<p>Error bars represent SD for n = 3 mice in each group. Statistical significance is indicated by * ...
<p>Antigen-specific antibody responses at week 4 (IgG—A, IgG1—B and IgG2a—C) and HI titer (D) at wee...
<p>Longitudinal measurements of (A) blood glucose and (B) serum IGF-1 in CH/XPA versus XPA and WT co...
<p><b>A, B.</b> Body weights of at least 8 mice per genotype per sex and time point were scored. The...
<p>(A) KD-fed mice showed lower blood glucose than controls on day 7 (***p<0.001). Animals in the K...
<p>B: Expression of IGF-II precursor (23 kDa) in muscle tissues from 11-, 29- and 54-week female Fzt...
<p>Average IOP of male mice was not significantly different between the 3 genotypes (<i>p>0</i>.<i>0...
<p>A, STZ injection resulted in elevated blood glucose levels in mice. B, Diabetic mice had lower bo...
<p>Male mice have increased spleen (A) and brain (B) fungal burden during chronic infection and incr...
<p>Mice were vaccinated with indicated doses. Four weeks later mice were sacrificed, and serum and B...
<p>Mice fed with a high AGE diet (n = 5) or a regular AGE diet (n = 5) for 26 and 39 weeks were anal...
<p>Four month old animals were fasted for 4 hours prior to sample collection. Values are represented...
<p>Hyperinsulinemic euglycemic clamp studies were conducted to calculate (A) Ginf, (B) GDR, (C) HGO,...
<p>The lengths of tibiae (A) and femora (B) from 33 weeks old mice with the indicated genotypes were...
<p>Similar blood glucose levels were observed with both groups of mice with levels higher in males t...
<p>Error bars represent SD for n = 3 mice in each group. Statistical significance is indicated by * ...
<p>Antigen-specific antibody responses at week 4 (IgG—A, IgG1—B and IgG2a—C) and HI titer (D) at wee...