<p>B: Expression of IGF-II precursor (23 kDa) in muscle tissues from 11-, 29- and 54-week female Fzt:DU and DU6P mice (n = 10 per age group). The results are normalized for the signal intensities as detected by Coomassie blue staining of the membranes used for Western immuno detection. Data are expressed as percent of female 11-week Fzt:DU mice (100%). The error bars represent SEM.</p
<p>(A) The relative content of IGF-I mRNA determined by qRT-PCR on gastrocnemius obtained at either ...
<p>IGF-I serum levels, body weight, as well as auditory brainstem response [hearing threshold, dB so...
To better characterize aging in mice, the Jackson Aging Center carried out a lifespan study of 31 ge...
<p>Western blot identified phosphorylated and total expression of the respective signaling molecule....
<p>Top: Biochemical analysis of glycogen content in muscle tissue of 29-week female Fzt:DU (n = 6) a...
<p>A: Western blot of muscle lysates in 11-, 29- and 54-week DU6P and Fzt:DU mice identified differe...
<p><b>A, B.</b> Blood serum from fasted mice at 12 weeks of age (more than 4 mice per group). IGF-1 ...
<p>The Western blot inserts show phosphorylated (Ser-473) and total expression of AKT from one repre...
<p>At 13 months of age, before there was any difference in body weight, food intake, feces output, a...
<p>Longitudinal measurements of (A) blood glucose and (B) serum IGF-1 in CH/XPA versus XPA and WT co...
<p>Body weight in A) female and B) male mice. Body weight was determined every third month during 3-...
<p>A: Phenotypes of female Fzt:DU and DU6P mice at the age of 11, 29 and 42 weeks. B: Success for th...
<p>Results are mean ± SD. Numbers in brackets denote the number of 2 to 3 mo old female mice examine...
<p>Antibody staining for IGF-1 and the IGF-1R showed no differences when comparing control and iLID ...
<p>A, Gender comparison of the percentage (y-axis) of EC within the CD45<sup>−</sup> population betw...
<p>(A) The relative content of IGF-I mRNA determined by qRT-PCR on gastrocnemius obtained at either ...
<p>IGF-I serum levels, body weight, as well as auditory brainstem response [hearing threshold, dB so...
To better characterize aging in mice, the Jackson Aging Center carried out a lifespan study of 31 ge...
<p>Western blot identified phosphorylated and total expression of the respective signaling molecule....
<p>Top: Biochemical analysis of glycogen content in muscle tissue of 29-week female Fzt:DU (n = 6) a...
<p>A: Western blot of muscle lysates in 11-, 29- and 54-week DU6P and Fzt:DU mice identified differe...
<p><b>A, B.</b> Blood serum from fasted mice at 12 weeks of age (more than 4 mice per group). IGF-1 ...
<p>The Western blot inserts show phosphorylated (Ser-473) and total expression of AKT from one repre...
<p>At 13 months of age, before there was any difference in body weight, food intake, feces output, a...
<p>Longitudinal measurements of (A) blood glucose and (B) serum IGF-1 in CH/XPA versus XPA and WT co...
<p>Body weight in A) female and B) male mice. Body weight was determined every third month during 3-...
<p>A: Phenotypes of female Fzt:DU and DU6P mice at the age of 11, 29 and 42 weeks. B: Success for th...
<p>Results are mean ± SD. Numbers in brackets denote the number of 2 to 3 mo old female mice examine...
<p>Antibody staining for IGF-1 and the IGF-1R showed no differences when comparing control and iLID ...
<p>A, Gender comparison of the percentage (y-axis) of EC within the CD45<sup>−</sup> population betw...
<p>(A) The relative content of IGF-I mRNA determined by qRT-PCR on gastrocnemius obtained at either ...
<p>IGF-I serum levels, body weight, as well as auditory brainstem response [hearing threshold, dB so...
To better characterize aging in mice, the Jackson Aging Center carried out a lifespan study of 31 ge...