D011-2120, but not G202-0362 inhibits RVFV Gn trafficking by disrupting the Golgi complex.

<p>HeLa cells were transduced to express a GFP-fused Golgi marker and were treated with (<b>A–C</b>) vehicle control (0.5% DMSO), (<b>D–F</b>) G202-0362 (20 µM), (<b>G–I</b>) D011-2120 (50 µM), (<b>J–L</b>) nocodazole (33 µM) at 2 h PI or (<b>M–O</b>) Brefeldin A(100 ng/mL) at 20 min before stopping the infection with RVFV MP12 strain (MOI = 10). Cells were fixed at 10 h PI and immuostained to detect RVFV Gn localization (Red) and stained with Hoechst 33342 to visualize nuclei (blue).