ML phylogenetic tree.

<p>A) HIV-1 subtype B <i>pol</i> PR/RT sequences (∼1,000 nt) circulating in the Caribbean (<i>n</i> = 743), US (<i>n</i> = 525), and France (<i>n</i> = 340); B) HIV-1 subtype B <i>pol</i> RT (∼600 nt) sequences from Barbados (<i>n</i> = 14), Guadeloupe (<i>n</i> = 243), Haiti (<i>n</i> = 15), Martinique (<i>n</i> = 452), Puerto Rico (<i>n</i> = 285), US Virgin Islands (<i>n</i> = 54) and representative sequences of the B_PANDEMIC (US = 165, France = 135) and the B_CAR (Caribbean = 200) clades. Branches are colored according to the geographic origin of each sequence as indicated at the legend (bottom right). Arcs indicate the B_PANDEMIC and B_CAR clades. Purple and green shaded boxes highlight the position of the Caribbean clades B_CAR-TT and B_CAR-JM. The <i>a</i>LRT support values are indicated at key nodes: *(0.81–0.90), **(0.91–1). Trees were rooted using HIV-1 subtype D reference sequences. The branch lengths are drawn to scale with the bar at the bottom indicating nucleotide substitutions per site.