Representative staining pattern of TIMP-3 protein expression in HCC and corresponding non-cancerous tissues in a tissue microarray (TMA).

<p>A1, A2 and A3. Negative immunohistochemical (IHC) staining of TIMP-3 in HCC samples. B1, B2 and B3. Positive IHC staining of TIMP-3 in HCC samples. The red arrow highlights positive staining in the cytoplasm of cancer cells. C1, C2 and C3. Negative IHC staining of TIMP-3 in non-cancerous tissue samples. D1, D2 and D3. Positive IHC staining of TIMP-3 in non-cancerous tissue samples. The blue arrow highlights positive staining in the cytoplasm of non-cancerous cells. Original magnification ×40 in A1, B1, C1 and D1; ×200 in A2, B2, C2 and D2; ×400 in A3, B3, C3 and D3.