<p>Histological Analysis of bone defects treated with Hydrogel and Hydrogel with CM, 45 days after implantation. <b>a</b>, <b>b</b>, hematoxylin and eosin staining, showing a mild chronic inflammatory response. <b>c</b>, <b>d</b>, blue toluidine staining, evidencing intramembranous ossification. <b>e</b>, <b>f</b>, Masson trichrome staining, showing a the organized and calcification of bone tissue.</p
<p>(A) Specimen of the 2-month complex, showing newly formed bone, connective tissue and bone marrow...
<p>Images show transversal sections carried out through the central area of the implants. A–C: crani...
<p>(A) The newly formed bone was stained in red color with visible cell nuclei by Van Gieson stainin...
<p>Bone defects treated with Hydrogel and Hydrogel with Ad-MSCs, 45 days after implantation. <b>a</b...
<p><b>A</b> Radiographic comparison of bone defects at 45 days with CM. <b>a.</b> Bone defect treate...
<p><b>A.</b> Surgical specimens 45 days after implantation of hydrogel with CM-1. <b>i</b>, initial ...
<p><b>A.</b> Radiographic comparison of bone defects at 45 days with different treatments. <b>a.</b>...
<p><b>A.</b> Surgical specimens 45 days after implantation. <b>a</b>. Hydrogel. <b>b.</b> Hydrogel w...
<p>Percentage of newly formed bone in defects treated with and without Ad-MSC (n = 4) and CM (n = 3)...
<p>S: scaffold, NB: new bone, OB: osteoblast, OC: osteocyte. EO: endochondral ossification. Scale Ba...
<p>(A) H&E staining of calvarial defects eight weeks after implantation of hASCs and/or periostin. H...
<p>(A): Isolated bone was formed at the peripheral area of the transplant material and far from the ...
<p>(A) Radiographic images of the treated defects (5 mm gap size) showing capping (arrows) of the co...
<p>(<b>A–F</b>) Haematoxylin and eosin staining. (<b>A</b>) Necrotic cortex with empty osseous lacun...
<p>New bone was visible in the area adjacent to the old bone and implanted scaffolds. Representative...
<p>(A) Specimen of the 2-month complex, showing newly formed bone, connective tissue and bone marrow...
<p>Images show transversal sections carried out through the central area of the implants. A–C: crani...
<p>(A) The newly formed bone was stained in red color with visible cell nuclei by Van Gieson stainin...
<p>Bone defects treated with Hydrogel and Hydrogel with Ad-MSCs, 45 days after implantation. <b>a</b...
<p><b>A</b> Radiographic comparison of bone defects at 45 days with CM. <b>a.</b> Bone defect treate...
<p><b>A.</b> Surgical specimens 45 days after implantation of hydrogel with CM-1. <b>i</b>, initial ...
<p><b>A.</b> Radiographic comparison of bone defects at 45 days with different treatments. <b>a.</b>...
<p><b>A.</b> Surgical specimens 45 days after implantation. <b>a</b>. Hydrogel. <b>b.</b> Hydrogel w...
<p>Percentage of newly formed bone in defects treated with and without Ad-MSC (n = 4) and CM (n = 3)...
<p>S: scaffold, NB: new bone, OB: osteoblast, OC: osteocyte. EO: endochondral ossification. Scale Ba...
<p>(A) H&E staining of calvarial defects eight weeks after implantation of hASCs and/or periostin. H...
<p>(A): Isolated bone was formed at the peripheral area of the transplant material and far from the ...
<p>(A) Radiographic images of the treated defects (5 mm gap size) showing capping (arrows) of the co...
<p>(<b>A–F</b>) Haematoxylin and eosin staining. (<b>A</b>) Necrotic cortex with empty osseous lacun...
<p>New bone was visible in the area adjacent to the old bone and implanted scaffolds. Representative...
<p>(A) Specimen of the 2-month complex, showing newly formed bone, connective tissue and bone marrow...
<p>Images show transversal sections carried out through the central area of the implants. A–C: crani...
<p>(A) The newly formed bone was stained in red color with visible cell nuclei by Van Gieson stainin...