Quantification of the CARS signal in human GBM.

<p><b>A</b>: Unprocessed CARS image of a cryosection of a human GBM specimen obtained during routine surgery. The CARS image displays the margin of a solid tumor and an infiltrative region. <b>B</b>: CARS signal intensity along the area indicated in panel A. The range of CARS signal intensity of normal tissue is underlined in green, of infiltrative areas in yellow, and of tumor in red, respectively. <b>C</b>: Dot plot showing the CARS signal intensity in normal gray matter vs. the intensity of the CARS signal in human GBM for each sample.