Reagents and conditions: (a) EDCI, HOBt, DIEA, CH<sub>2</sub>Cl<sub>2</sub>, room temp, 4 h, 90%; (b) (i) Pd(TFA)<sub>2</sub>, BINAP, Cs<sub>2</sub>CO<sub>3</sub>, toluene, 80°C, 8 h, and (ii) AcOH, Fe powder, reflux, 2 h (60% for 2 steps); (c) 1,4-dioxane, 4N HCl, reflux, 2 h, 80%.
- Ganipisetti Srinivasrao (628526)
- Jung-Eun Park (480566)
- Sungmin Kim (628527)
- Mija Ahn (480558)
- Chaejoon Cheong (410995)
- Ky-Youb Nam (489842)
- Pethaiah Gunasekaran (628528)
- Eunha Hwang (480562)
- Nam-Hyung Kim (293371)
- Song Yub Shin (480564)
- Kyung S. Lee (271991)
- Eunkyung Ryu (628529)
- Jeong Kyu Bang (480567)
Publication date
September 2014
DOIAbstract
<p>Reagents and conditions: (a) EDCI, HOBt, DIEA, CH<sub>2</sub>Cl<sub>2</sub>, room temp, 4 h, 90%; (b) (i) Pd(TFA)<sub>2</sub>, BINAP, Cs<sub>2</sub>CO<sub>3</sub>, toluene, 80°C, 8 h, and (ii) AcOH, Fe powder, reflux, 2 h (60% for 2 steps); (c) 1,4-dioxane, 4N HCl, reflux, 2 h, 80%.</p
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