<p><i><sup>a</sup></i>Reagents and conditions: a) Tosylmethylisocyanate, Na<sub>2</sub>CO<sub>3</sub>, Methanol, Reflux, 4 hours; b) Cs<sub>2</sub>CO<sub>3</sub>, Pd(dppf)Cl<sub>2</sub>, DMF/Water; Reflux, 15 hours; c) Na<sub>2</sub>CO<sub>3</sub>, Pd(PPh<sub>3</sub>)<sub>4</sub>, Dioxane/Water, 90°C, 48 hours; d) Cs<sub>2</sub>CO<sub>3</sub>, Pd(dppf)Cl<sub>2</sub>, DMF/Water; Reflux, 15 hours.</p
<p>Synthesis of 14: Reagents and conditions: (a) 4-phenyl butyl bromide, K<sub>2</sub>CO<sub>3</sub>...
<p>Reagents and conditions: (a) R<sup>2</sup>CH<sub>2</sub>OH, NaH, THF, reflux; (b) R<sup>2</sup>CH...
<p>Reagents and conditions: i) Hydrazine sulphate, H<sub>2</sub>O, 100°C; ii) Pyridin-4-ylboronic ac...
<p>Reagents and conditions: (i) Na<sub>2</sub>CO<sub>3</sub>, (PPh<sub>3</sub>)<sub>2</sub>PdCl<sub>...
<p><i>Reagent</i>s: <b>i</b>: NH<sub>2</sub>NH<sub>2</sub><sup>.</sup>H<sub>2</sub>O, EtOH, reflux, ...
<p><i><sup>a</sup></i>Reagents and conditions: a) nBuLi, diethyl ether, −78°C, 60 min; trimethylsily...
<p>Reagents and Conditions: (a) Ethyl 3-bromobutyrate, Cs<sub>2</sub>CO<sub>3</sub>, MeCN, reflux, 2...
<p><i>Reagents and conditions</i>: (i) SOCl<sub>2</sub>, MeOH, r.t., 2.5 h, reflux 30 min, r.t. 4 h,...
<p>Reagents and conditions: a. TsOH, ethanol; 0°C, NaBH<sub>4</sub>; b. K<sub>2</sub>CO<sub>3</sub>,...
Reagents and conditions: a) for 2a-c: HCl·H2NO(CH2)nCOOH, acetic acid, 80 °C, 3h; for 2d: HCl·H2NO(C...
<p>Reagent and conditions: (a) Conc. H<sub>2</sub>SO<sub>4</sub>, MeOH, 0°C to rt, 6 hrs. (b) pallad...
<p>Reagents and conditions: (a) CH<sub>2</sub>Cl<sub>2</sub>, r.t, overnight.</p
<p>Reagents and conditions: (a) CH<sub>2</sub>Cl<sub>2</sub>, r.t, overnight.</p
<p>Reagents and conditions: i) from <b>1</b> for <b>23</b>, from <b>5</b> for <b>24</b>, from <b>32<...
<p>Reagents and conditions: (a) EDCI, HOBt, DIEA, CH<sub>2</sub>Cl<sub>2</sub>, room temp, 4 h, 90%;...
<p>Synthesis of 14: Reagents and conditions: (a) 4-phenyl butyl bromide, K<sub>2</sub>CO<sub>3</sub>...
<p>Reagents and conditions: (a) R<sup>2</sup>CH<sub>2</sub>OH, NaH, THF, reflux; (b) R<sup>2</sup>CH...
<p>Reagents and conditions: i) Hydrazine sulphate, H<sub>2</sub>O, 100°C; ii) Pyridin-4-ylboronic ac...
<p>Reagents and conditions: (i) Na<sub>2</sub>CO<sub>3</sub>, (PPh<sub>3</sub>)<sub>2</sub>PdCl<sub>...
<p><i>Reagent</i>s: <b>i</b>: NH<sub>2</sub>NH<sub>2</sub><sup>.</sup>H<sub>2</sub>O, EtOH, reflux, ...
<p><i><sup>a</sup></i>Reagents and conditions: a) nBuLi, diethyl ether, −78°C, 60 min; trimethylsily...
<p>Reagents and Conditions: (a) Ethyl 3-bromobutyrate, Cs<sub>2</sub>CO<sub>3</sub>, MeCN, reflux, 2...
<p><i>Reagents and conditions</i>: (i) SOCl<sub>2</sub>, MeOH, r.t., 2.5 h, reflux 30 min, r.t. 4 h,...
<p>Reagents and conditions: a. TsOH, ethanol; 0°C, NaBH<sub>4</sub>; b. K<sub>2</sub>CO<sub>3</sub>,...
Reagents and conditions: a) for 2a-c: HCl·H2NO(CH2)nCOOH, acetic acid, 80 °C, 3h; for 2d: HCl·H2NO(C...
<p>Reagent and conditions: (a) Conc. H<sub>2</sub>SO<sub>4</sub>, MeOH, 0°C to rt, 6 hrs. (b) pallad...
<p>Reagents and conditions: (a) CH<sub>2</sub>Cl<sub>2</sub>, r.t, overnight.</p
<p>Reagents and conditions: (a) CH<sub>2</sub>Cl<sub>2</sub>, r.t, overnight.</p
<p>Reagents and conditions: i) from <b>1</b> for <b>23</b>, from <b>5</b> for <b>24</b>, from <b>32<...
<p>Reagents and conditions: (a) EDCI, HOBt, DIEA, CH<sub>2</sub>Cl<sub>2</sub>, room temp, 4 h, 90%;...
<p>Synthesis of 14: Reagents and conditions: (a) 4-phenyl butyl bromide, K<sub>2</sub>CO<sub>3</sub>...
<p>Reagents and conditions: (a) R<sup>2</sup>CH<sub>2</sub>OH, NaH, THF, reflux; (b) R<sup>2</sup>CH...
<p>Reagents and conditions: i) Hydrazine sulphate, H<sub>2</sub>O, 100°C; ii) Pyridin-4-ylboronic ac...