Deficiency of ERdj4 increases cell death during B lymphopoiesis.

<p>Developing B cells were stained with 7-AAD and analyzed by flow cytometry. (A) Representative histograms from flow cytometric analyses of B cell progenitors positive for 7-AAD. Numbers indicate frequency of gated population for each genotype. (B) Average frequencies of 7-AAD⁺ B cell progenitors. <i>n</i> = 7–8 mice/genotype. Pro-B, IgM⁻CD19⁺B220⁺CD43⁺FSC^low; Large pre-B, IgM⁻CD19⁺B220⁺CD43⁺FSC^high; Small pre-B, IgM⁻B220⁺CD43⁻; IMB, B220^lowIgM⁺.