Differential miRNAs between Elite Controllers (EC) and Viremic Progressors (VP).

<p>A) Hierarchical clustering of the differentially expressed miRNAs between EC and VP. Patients are ordered on vertical lines and candidate miRNAs on horizontal lines. For each miRNA, green represents under-expressed and red over-expressed values compared to the average value (median), in dark. Dendrograms (tree graph) between patients and between miRNAs are depicted, where the closest branches of the tree represent patients/miRNAs with the most similar expression pattern. Two blocks of patients (Block 1/Block 2) with an inverse expression profile were segregated. Two groups of miRNAs (Group 1/Group 2) with an inverse expression profile were segregated within each block. B) Fold change (log 2) of the 23 differentially expressed miRNAs in EC. Differential levels are normalized to all assesed miRNAs and relative to VP. Bars represent standard error means (SEM).