<p>Secondary challenge bacteria segregate into the liver and spleen to form independent populations within 6 h. Subsequently hepatic and splenic populations become homogeneous from 120 h. All WITS within a mouse are represented by the same symbol. Points along the diagonal correspond to equal abundances in both organs. Mice were either controls or depleted of T-cells (T−); they all received the live vaccine and were challenged with 310 CFU of WITS.</p
<p>Following infection with V and Ts, the spleen (A), MLN and blood from three mice per group per ti...
<p>B6 mice were inoculated i.p. with 1×10<sup>4</sup> pfu of either C4C, K181 or K181<sup>Δm157</sup...
<p>T-cell depleted mice fail to restrain growth of secondary challenge bacteria from 72 h p.i. Bacte...
<p>Secondary challenge bacteria segregate into the liver and spleen to form independent populations ...
<p>T-cell dependent bactericidal activity is evident in LV-immunised mice by 120 h post-rechallenge;...
<p>Percentage of T-cell depleted (T−) or T-cell positive (T+) live-vaccine immunised mice exhibiting...
<p>(A) C57BL/6 mice were orally infected with a mixture of 10 individually tagged WITS. Two days aft...
<p>C57BL/6 mice were orally vaccinated with attenuated SL1344Δ<i>aro</i>A <i>Salmonella</i> Typhimur...
<p>Mice were oral gavaged with 10<sup>8</sup><i>S.</i> Typhimurium consisting of an equal mixture of...
<p>Mice were infected with a 1:1:1 mixture of 3 resistance marker tagged NewHG variants and 5 mice s...
<p>Streptomycin-pretreated C57BL/6 mice were gavaged with a mixture of 7 WITS strains in equal ratio...
<p>Live vaccine but not killed vaccine controls bacterial loads following secondary challenge. Bacte...
<p>Mice were vaccinated with a SL1344Δ<i>aroA</i> strain 40–50 days or left untreated before infecti...
<p>Streptomycin-pretreated C57BL/6 mice were orally infected with a WITS cocktails in the dilution 1...
<p>Mice were infected with a 1∶1∶1 mixture of three marked <i>S. aureus</i> NewHG strains (n = 8–10 ...
<p>Following infection with V and Ts, the spleen (A), MLN and blood from three mice per group per ti...
<p>B6 mice were inoculated i.p. with 1×10<sup>4</sup> pfu of either C4C, K181 or K181<sup>Δm157</sup...
<p>T-cell depleted mice fail to restrain growth of secondary challenge bacteria from 72 h p.i. Bacte...
<p>Secondary challenge bacteria segregate into the liver and spleen to form independent populations ...
<p>T-cell dependent bactericidal activity is evident in LV-immunised mice by 120 h post-rechallenge;...
<p>Percentage of T-cell depleted (T−) or T-cell positive (T+) live-vaccine immunised mice exhibiting...
<p>(A) C57BL/6 mice were orally infected with a mixture of 10 individually tagged WITS. Two days aft...
<p>C57BL/6 mice were orally vaccinated with attenuated SL1344Δ<i>aro</i>A <i>Salmonella</i> Typhimur...
<p>Mice were oral gavaged with 10<sup>8</sup><i>S.</i> Typhimurium consisting of an equal mixture of...
<p>Mice were infected with a 1:1:1 mixture of 3 resistance marker tagged NewHG variants and 5 mice s...
<p>Streptomycin-pretreated C57BL/6 mice were gavaged with a mixture of 7 WITS strains in equal ratio...
<p>Live vaccine but not killed vaccine controls bacterial loads following secondary challenge. Bacte...
<p>Mice were vaccinated with a SL1344Δ<i>aroA</i> strain 40–50 days or left untreated before infecti...
<p>Streptomycin-pretreated C57BL/6 mice were orally infected with a WITS cocktails in the dilution 1...
<p>Mice were infected with a 1∶1∶1 mixture of three marked <i>S. aureus</i> NewHG strains (n = 8–10 ...
<p>Following infection with V and Ts, the spleen (A), MLN and blood from three mice per group per ti...
<p>B6 mice were inoculated i.p. with 1×10<sup>4</sup> pfu of either C4C, K181 or K181<sup>Δm157</sup...
<p>T-cell depleted mice fail to restrain growth of secondary challenge bacteria from 72 h p.i. Bacte...