Gene expression profiles of (A) TRPV1 receptor, sensory neuropeptides, such as (B) PACAP, (C) VIP, and their receptors (D) PAC1R, (E) VIPR1, (F) VIPR2, as well as another sensory neuropeptide (G) somatostatin and its receptors (H) SSTR1, (I) SSTR4, and tachykinins (J) TAC 1, (K) TAC 3, as well as their receptor NK1.

<p>Gene expression was determined in the distal colon homogenates of water-treated non-inflamed wildtype (WT) and TRPA1-deficient (Trpa1 KO) mice, as well as after 3, 7 and 10 days of dextran-sulphate (DSS) determined by multiplex bead array. Columns represent means±SEM. *p<0.05, **p<0.01 vs. respective water-receiving control; #p<0.05, #p<0.01 WT vs. KO (n = 3-5/group, Mann-Whitney U test).