CCR5+ cells accumulate in the inner foreskin in from sexually active MSM.

<p>A) Representative images of foreskin epidermis at 10× magnification stained with CCR5 (pseudocolored green), CD4 (pseudocolored red) and SYTOX Orange (pseudocolored blue) for nuclear identification. All fields from ∼26.5 mm² sections were used for analysis. For isotype controls and larger tissue sections see <b><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0108954#pone.0108954.s001" target="_blank">Figure S1</a></b>. White letters mark CD4+ cell aggregates (A), and epidermis (E). B–G) Cell density measured in the B, D, F) whole tissue (dermis and epidermis) or C, E, G) epidermis. Cell types measured are B, C) CD4+, D, E) CCR5+ and F, G) CD4+ CCR5+ cells. All p-values are from FDR-adjusted Wilcoxon tests.