Sexually active MSM have a slightly reduced SC envelope in the inner foreskin.

<p>A) Median SC thickness (µm) was computed from 3–5 sections of inner/outer foreskin, each taken 5 mm apart. B) Involucrin and C) keratin 1,10 levels were measured by MBA in foreskin lysates. All p values are from FDR-adjusted Wilcoxon comparisons of all subjects sexually active within the past 2 weeks (n = 17).