<p>GAMT KO (n = 4) with the age and sex matched corresponding wild-type (GAMT WT) mice (n = 4; female). (<b>B</b>) Effect of 0.5 µM H<sub>2</sub>O<sub>2</sub> on cardiac function during 30 min exposure in isolated perfused Cr-T overexpressing (CrT-OE) hearts (n = 7; 7 female) and age matched wild-type (CrT-WT) controls (n = 4; female). RPP- rate pressure product. *P<0.05 vs WT. Data mean±S.E.M. P value is for the effect of the genotype by ANOVA with Bonferroni’s correction.</p
(A) The HW/BW ratio between male Sirt5 KO mice and WT littermates at 5 weeks after TAC surgery (n = ...
<p>A) Left-ventricular weight (LV-W) to tibia length (TL)in adult Wt and Tg mice subjected to saline...
<p>Left ventricular fractional shortening (A) and ejection fraction (B) as determined by echocardiog...
<p>GAMT KO (n = 8; male); WT (n = 5; 3 female+2 male) (<b>B</b>) isolated perfused CrT overexpressin...
<p>(<b>B</b>) Protective effect of catalase against H<sub>2</sub>O<sub>2</sub>–induced function dete...
<p>Group S are untreated wild-type sham-operated mice; Group MI are untreated wild-type infarcted mi...
<p>A) The effect of chronic hypoxia on right ventricular systolic blood pressure (RVSBP) in wild typ...
The Langendorff mouse heart model is widely employed in studies of myocardial function and responses...
<p>A) GAG storage in hearts from 8-month old normal (n = 3), MPS I (n = 5) and MPS I mice treated wi...
<p>Cardiac levels of GLO-1 protein (A), GLO-1 activity (B), CML (C), CEL (D), and MG-H1 (E) in non-d...
<p>(A) Fractional shortening (FS%) was monitored by echocardiography under basal conditions at eight...
<p>(a) Comparison of the heart/body weight ratios obtained from each genotype showed that cardiac hy...
<p>(A) Two weeks of chronic ISO infusion significantly increased the heart weight to tibia length-ra...
<p>Baseline (A) MAP and (B) HR were measured (D1-N3) in EC-MR KO and WT mice (n = 14–18 per group). ...
<p>A) Longitudinal measurements of cardiac index (CI) in homo-βthal mice (filled bars) at ages 6, 10...
(A) The HW/BW ratio between male Sirt5 KO mice and WT littermates at 5 weeks after TAC surgery (n = ...
<p>A) Left-ventricular weight (LV-W) to tibia length (TL)in adult Wt and Tg mice subjected to saline...
<p>Left ventricular fractional shortening (A) and ejection fraction (B) as determined by echocardiog...
<p>GAMT KO (n = 8; male); WT (n = 5; 3 female+2 male) (<b>B</b>) isolated perfused CrT overexpressin...
<p>(<b>B</b>) Protective effect of catalase against H<sub>2</sub>O<sub>2</sub>–induced function dete...
<p>Group S are untreated wild-type sham-operated mice; Group MI are untreated wild-type infarcted mi...
<p>A) The effect of chronic hypoxia on right ventricular systolic blood pressure (RVSBP) in wild typ...
The Langendorff mouse heart model is widely employed in studies of myocardial function and responses...
<p>A) GAG storage in hearts from 8-month old normal (n = 3), MPS I (n = 5) and MPS I mice treated wi...
<p>Cardiac levels of GLO-1 protein (A), GLO-1 activity (B), CML (C), CEL (D), and MG-H1 (E) in non-d...
<p>(A) Fractional shortening (FS%) was monitored by echocardiography under basal conditions at eight...
<p>(a) Comparison of the heart/body weight ratios obtained from each genotype showed that cardiac hy...
<p>(A) Two weeks of chronic ISO infusion significantly increased the heart weight to tibia length-ra...
<p>Baseline (A) MAP and (B) HR were measured (D1-N3) in EC-MR KO and WT mice (n = 14–18 per group). ...
<p>A) Longitudinal measurements of cardiac index (CI) in homo-βthal mice (filled bars) at ages 6, 10...
(A) The HW/BW ratio between male Sirt5 KO mice and WT littermates at 5 weeks after TAC surgery (n = ...
<p>A) Left-ventricular weight (LV-W) to tibia length (TL)in adult Wt and Tg mice subjected to saline...
<p>Left ventricular fractional shortening (A) and ejection fraction (B) as determined by echocardiog...