EBNA-3A does not repress p14^ARF or p16^INK4a expression in in Wp-R BL.

<p>The levels of p14^ARF and p16^INK4a in Sal BL were analyzed at 4 days post-transfection and not detected. Sal cells were transfected in duplicate with expression vectors for either EBNA-3A-specific shRNA 1490 or 601, control shRNA (C2) or empty vector (oriP). Saos2 and MCF7 serve as positive controls for detection of p14^ARF and p16^INK4a; GAPDH, loading control. Knockdown of EBNA-3A was similar to that shown in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1004415#ppat-1004415-g002" target="_blank">Figure 2A</a>.