Optineurin protein sequences are conserved across species.

<p>Alignment of optineurin protein sequences from human, mouse and zebrafish. Black shaded amino acids are conserved across species, gray shaded amino acids are similar. Identified protein binding sites are indicated above the corresponding parts of the protein. Asterisks indicated amino acids associated with disease in human patients when mutated. Number sign indicates location of <i>sa0143</i> zebrafish mutation.