Mouse multiplex array cytokine assay was performed on protein extracts from acute inflamed (day 6 post-infection) brain and spinal cord tissues from RSA59-infected and mock-infected mice.

<p>Expression levels of pro- and anti-inflammatory cytokines reveals up-regulation of proteins involved in innate immune responses, including IFN-γ, IL-12, IL-10 and mKC, similar to gene expression data. (* Represents significant upregulation. P values for IFN-γ is <0.002, for IL-10 is <0.005, for IL-12 is <0.004 and for mKC is <0.005).