Histological analysis of 10-day old implants from non-diabetic and diabetic rats.

<p>Representative histological sections stained with H&E of fibrovascular tissue from diabetic (A) and non diabetic (B) rats. The pores of the sponge matrix, seen as triangular shapes, is composed of microvessels (C), spindle-shaped fibroblasts (D) and inflammatory infiltrate consisting of neutrophils (E), macrophages (F), and foreign body giant cells (G). Dilated microvessels and low cellularity were characteristics of implants from diabetic rats (H). Data are expressed as means ± SEM. *Significant difference between non-diabetic and diabetic; p<0.05; Mann-Whitney test. NSC, non-diabetic implant; DSC, diabetic implant; scale bar, 50 µm.