Vascularization in 10-day old implants from non-diabetic and diabetic rats.

<p>Hemoglobin content (A) and VEGF levels (B), both angiogenic markers, were not altered after diabetes induction. Morphometric analysis showed a decreased number of blood vessels in implants from diabetic as compared with non-diabetic rats (C). Representative CD31-immunostained section shows the newly formed vascular structures (D). Values shown are expressed as mean±SEM. *Significant difference between non-diabetic and diabetic; p<0.05. Student's t-test. NSC, non-diabetic implant; DSC, diabetic implant; scale bar, 25 µm.