<p>(A) HγD-crys incubated at pH 2.0, 37°C for 1 hr; (B) HγD-crys incubated at pH 2.0, 55°C for 1 hr; (C) HγD-crys incubated at pH 7.0, 37°C for 1 hr; and (D) HγD-crys incubated at pH 7.0, 55°C for 1 hr. Aggregation formed under pH 2.0 conditions resembles fibril morphology, while retaining granular appearance under pH 7.0 conditions. The scale bar represents 100 nm.</p
Yellow arrows indicate correctly assembled NPs. Red arrows indicate incorrectly structured NPs like ...
<p>Pathogenic mutant E196K (A and B) and D178N (C and D) samples were incubated for 8 h (A and C) or...
<p>(A) Aβ 1–42 fibrils alone. (B) Aβ 1–42 fibrils after co-incubation with D19. A number of laterall...
<p>Fibrils formed from 60 µM peptides in phosphate buffer, pH 7.0, 37°C on day 5. All TEM images are...
<p>Negative stain TEM images taken from aggregation mixtures at different times: After 2 minutes, in...
<p>(A) ThT fluorescence for CT at pH 6.0, 5.7, 5.5, 5.3, and 5.0, and NT at pH 5.0, in sodium acetat...
<p>Observed morphology of HEWL aggregates after incubation in pH 12.2 (unless indicated otherwise) f...
<p>2 mg/ml PAP248-286 was incubated in the presence or absence of 30 µg/ml polyanions. The amyloid f...
A procedure is presented for the preparation of thin layers of vitrified biological suspensions in t...
<p>Negative stain EM of shaking-induced prion oligomers (panel A) and fibrils (panel B). The oligome...
<p>A) and B) desmin tetramers. A) the use of a multivalent ion as staining agent induced the formati...
Recent advances in electron microscopy and image analysis techniques have resulted in the developmen...
<p>The 250,000×g pellet 4 prepared from the caput (a–e) and corpus-cauda epididymal luminal fluid (f...
<p>ApoAI-Milano (R173C), apoAI-WT and apoAI-Iowa (G26R) proteins were incubated at 37°C for four wee...
<p>Hen lysozyme samples were incubated for 14 days in the absence of a crowding agent (A) and in the...
Yellow arrows indicate correctly assembled NPs. Red arrows indicate incorrectly structured NPs like ...
<p>Pathogenic mutant E196K (A and B) and D178N (C and D) samples were incubated for 8 h (A and C) or...
<p>(A) Aβ 1–42 fibrils alone. (B) Aβ 1–42 fibrils after co-incubation with D19. A number of laterall...
<p>Fibrils formed from 60 µM peptides in phosphate buffer, pH 7.0, 37°C on day 5. All TEM images are...
<p>Negative stain TEM images taken from aggregation mixtures at different times: After 2 minutes, in...
<p>(A) ThT fluorescence for CT at pH 6.0, 5.7, 5.5, 5.3, and 5.0, and NT at pH 5.0, in sodium acetat...
<p>Observed morphology of HEWL aggregates after incubation in pH 12.2 (unless indicated otherwise) f...
<p>2 mg/ml PAP248-286 was incubated in the presence or absence of 30 µg/ml polyanions. The amyloid f...
A procedure is presented for the preparation of thin layers of vitrified biological suspensions in t...
<p>Negative stain EM of shaking-induced prion oligomers (panel A) and fibrils (panel B). The oligome...
<p>A) and B) desmin tetramers. A) the use of a multivalent ion as staining agent induced the formati...
Recent advances in electron microscopy and image analysis techniques have resulted in the developmen...
<p>The 250,000×g pellet 4 prepared from the caput (a–e) and corpus-cauda epididymal luminal fluid (f...
<p>ApoAI-Milano (R173C), apoAI-WT and apoAI-Iowa (G26R) proteins were incubated at 37°C for four wee...
<p>Hen lysozyme samples were incubated for 14 days in the absence of a crowding agent (A) and in the...
Yellow arrows indicate correctly assembled NPs. Red arrows indicate incorrectly structured NPs like ...
<p>Pathogenic mutant E196K (A and B) and D178N (C and D) samples were incubated for 8 h (A and C) or...
<p>(A) Aβ 1–42 fibrils alone. (B) Aβ 1–42 fibrils after co-incubation with D19. A number of laterall...