CT forms amyloid-like fibrils at low pH.
- Marlene Andersson (610369)
- Gefei Chen (111998)
- Martins Otikovs (610370)
- Michael Landreh (610371)
- Kerstin Nordling (610372)
- Nina Kronqvist (411936)
- Per Westermark (79625)
- Hans Jörnvall (289557)
- Stefan Knight (610373)
- Yvonne Ridderstråle (610374)
- Lena Holm (243553)
- Qing Meng (112017)
- Kristaps Jaudzems (610375)
- Mitchell Chesler (610376)
- Jan Johansson (112011)
- Anna Rising (112014)
Publication date
August 2014
DOIAbstract
<p>(A) ThT fluorescence for CT at pH 6.0, 5.7, 5.5, 5.3, and 5.0, and NT at pH 5.0, in sodium acetate buffer. (B) Transmission electron micrograph showing fibrils formed from CT incubated at pH 5.5. Scale bar, 200 nm. (C) Congo red stained fibrils formed by CT at pH 5.5, viewed under crossed polarizers. Green birefringence is visible. Scale bar, 50 µm.</p
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