Intracellular fluctuations in 2D vs. 3D.

<p>a,b) 1D mitochondria MSDs in the two orthogonal directions with maximum ratio in displacement fluctuations for cells in (a) 2D and (b) 3D. Larger slopes (more fluid-like behavior) and magnitudes are exhibited by cells in 2D at longer time intervals. c,d) Logarithmic time derivative β of MSDs for cells in (c) 2D and (d) 3D in the corresponding 1D directions. Cells in 3D have lower β's, indicating more solid-like behavior. Error bars are s.e.m. The color code of the curves is the same as in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1003959#pcbi-1003959-g002" target="_blank">Figure 2b</a>.