Overexpression of miR-33b inhibits proliferation, migration and invasion of osteosarcoma cells.

<p>(A) qRT-PCR analysis of miR-33b expression after the transfection of miR-33b mimics, inhibitors or scramble or untreated. (B) The CCK8 assay used to evalute the proliferation of MG-63 cells after transfection with the miR-33b mimics, inhibitors or scramble or untreated. (C) Migration assays of MG-63 cells after treatment with miRNA mimics, inhibitors or scramble or no transfection; the relative ratio of migrative cells per field is shown. (D) Invasion analysis of MG-63 cells after treatment with miRNA mimics, inhibitors or scramble or no untreated; the relative ratio of invasive cells per field is shown below, least significant difference (LSD) test was used to analyze the significant differences. *p<0.05, ** p<0.01, and ***p<0.001.