TG mice hearts show decreased ISO response.
- Mayilvahanan Shanmugam (691549)
- Dan Li (106345)
- Shumin Gao (106962)
- Nadezhda Fefelova (481255)
- Vikas Shah (691550)
- Antanina Voit (667565)
- Ronald Pachon (691551)
- Ghassan Yehia (266316)
- Lai-Hua Xie (61988)
- Gopal J. Babu (667567)
Publication date
February 2015
DOIAbstract
<p><b>(A)</b> Representative M-mode echocardiographic images of the left ventricle in NTG and TG mice at baseline and post ISO (0.04μg/Kg/min) infusion. <b>(B)</b> Dose response curves showing the changes in heart rate (HR) and <b>(C)</b> ejection fraction (EF) after infusion of ISO at 0.02 and 0.04 μg/Kg/min in the TG and NTG mice. *NTG vs. TG; p<0.05, ** NTG vs. TG; p<0.005, <sup>#</sup>baseline vs. ISO (0.04 μg); p<0.05.</p
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