<p>Dscore values, volume sizes, hydrophilic and hydrophobic areas of the five binding sites in three IL-1R1 crystal structures (PDB entries: 4GAF, 1IRA and 1G0Y) identified by the Sitemap program.</p
<div><p>The residue composition of a ligand binding site determines the interactions available for d...
<p>Representation of binding sites of HCI.SDF1α and commercial antibodies on full-length SDF-1α and ...
<p><i>Size</i> indicates the number of alpha spheres comprising the site. <i>PLB</i> is the Propensi...
<p>Binding sites with the Dscore value ≥ 0.83 are shown in bold font.</p><p>Dscore values, Volume si...
<p>S1-S5 denote the binding site number in each conformation and the arrows point to their locations...
<p>(A) Dscore values and Site volumes detected in <b>N1</b>-<b>N9</b> and <b>M1</b>-<b>M8</b> where ...
<p>The top panel depicts results with the original crystal structures used rigidly, with a red line ...
<p>The vanilla color regions correspond to the binding sites with Dscore value ≥ 0.83.</p
<p>(A-C), druggable sites (Dscore values ≥ 0.83) in 25 representative conformations. Consensus bindi...
<p>In all panels aminoacid numbering refers to the human protein. (A) Left: ribbon diagram of the ex...
The sc-PDB is a collection of 6 415 three-dimensional structures of binding sites found in the Prote...
<p><b>(a)</b> Structural alignment of the FM (grey) and IL-1β (6I1B; cyan). Several loops of IL-1β a...
<p><b>A.</b> Overall distribution of experimental and predicted complexes on the pathway. Dark blue ...
Alignments of high-scoring binding site pairs of the Barelier data set generated by (A) Cavbase, (B)...
<p>Persistence of clefts A–I among A1AT crystal structures (A) and computationally produced conforme...
<div><p>The residue composition of a ligand binding site determines the interactions available for d...
<p>Representation of binding sites of HCI.SDF1α and commercial antibodies on full-length SDF-1α and ...
<p><i>Size</i> indicates the number of alpha spheres comprising the site. <i>PLB</i> is the Propensi...
<p>Binding sites with the Dscore value ≥ 0.83 are shown in bold font.</p><p>Dscore values, Volume si...
<p>S1-S5 denote the binding site number in each conformation and the arrows point to their locations...
<p>(A) Dscore values and Site volumes detected in <b>N1</b>-<b>N9</b> and <b>M1</b>-<b>M8</b> where ...
<p>The top panel depicts results with the original crystal structures used rigidly, with a red line ...
<p>The vanilla color regions correspond to the binding sites with Dscore value ≥ 0.83.</p
<p>(A-C), druggable sites (Dscore values ≥ 0.83) in 25 representative conformations. Consensus bindi...
<p>In all panels aminoacid numbering refers to the human protein. (A) Left: ribbon diagram of the ex...
The sc-PDB is a collection of 6 415 three-dimensional structures of binding sites found in the Prote...
<p><b>(a)</b> Structural alignment of the FM (grey) and IL-1β (6I1B; cyan). Several loops of IL-1β a...
<p><b>A.</b> Overall distribution of experimental and predicted complexes on the pathway. Dark blue ...
Alignments of high-scoring binding site pairs of the Barelier data set generated by (A) Cavbase, (B)...
<p>Persistence of clefts A–I among A1AT crystal structures (A) and computationally produced conforme...
<div><p>The residue composition of a ligand binding site determines the interactions available for d...
<p>Representation of binding sites of HCI.SDF1α and commercial antibodies on full-length SDF-1α and ...
<p><i>Size</i> indicates the number of alpha spheres comprising the site. <i>PLB</i> is the Propensi...
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