Gene Ontology (GO) term enrichments in modules identified by WGCNA and in randomly generated modules.

<p>(<b>A</b>) Molecular function and (<b>B</b>) biological process GO terms. Line plots represent the number of enriched modules as a function of the number of enriched terms in a module. Red symbols represent the observed counts, and red lines represent the best smooth of the data points. The black lines and symbols represent the mean number of enriched modules for modules with any given number of enriched GO terms in 100 random replicates. The boxplot represents the number of total modules with at least one enriched term in all 100 random permutations of the network. Red symbols represent the number of modules with at least one enriched term in the natural network. Real BP data included eight modules enriched for up to 274 terms, which were not shown in the figure.