Top GWAS SNP hits in genes of functional relevance for BMI, organized by chromosome.

<p>Results are for GWAS analysis in GenABEL using each individual BMI reading as a separate observation, modelling the correlation between readings via the estimated kinship and using the Genomic Control deflation factor to avoid inflation of the overall distribution of test statistics. Results are for allele-wise tests under an additive model of inheritance for genotyped SNPs and for imputed data. Bold indicates the top hit for BMI based on both genotyped and 1000G imputed data. Full lists of the top 50 hits for genotyped SNPs, and the top 100 SNPs for imputed data, appear in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0119333#pone.0119333.s012" target="_blank">S3 Table</a> and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0119333#pone.0119333.s015" target="_blank">S6 Table</a>, respectively.</p><p>* Genes separated by forward slash indicate nearest protein coding genes upstream/downstream of the SNP. NCBI37 = bp location on chromosome for NCBI Build 37. A1 = major allele; A2 = minor allele.</p><p>Top GWAS SNP hits in genes of functional relevance for BMI, organized by chromosome.