<p>(<b>A</b>) Chitinase enzyme activity of recombinant enzymes or lung homogenates from 14 days post-infected or naïve mice. (<b>B</b>) Flow cytometry plots of CD4+, Foxp3-, CD44+ Cda2+ Th cells expressing Th2 cytokines, IL-5 & IL-13, at 14 days post-infection and (<b>C</b>) the quantification of these plots. (<b>D&E</b>) Survival of mutant or wildtype mice infected with KN99α either with or without IL-2 complex treatment. Logrank test comparing each survival curve relative with 10 mice for each group to: Chit1 −/− vs. wildtype, <i>P</i><0.005; Chit1 −/− vs. Chit1 −/− + IL-2 complex, <i>P</i><0.0005; Chit1 −/− + IL-2 complex vs. wildtype, <i>P</i> = 0.07. (<b>F</b>) Cytokines from lung homogenates of naïve or wildtype and Chit1−/− mice 14 d...
Background: Chitinolytic enzymes play important roles in the pathophysiology of allergic airway resp...
Pulmonary mycoses are often associated with type-2 helper T (Th2) cell responses. Howev-er, mechanis...
<p>(<b>A</b>) Cda2-MHCII tetramer identifies <i>C. neoformans</i>-specific helper T (Th) cells from ...
<p><b>1</b>) Chitotriosidase is released by the host and degrades fungal chitin to generate small ch...
Contains fulltext : 172746.pdf (publisher's version ) (Open Access)Chitotriosidase...
<p>(A-C) The BALB/c mice were intraperitoneally injected for 3 times at 7-day intervals with in-vitr...
Pulmonary mycoses are often associated with type-2 helper T (Th2) cell responses. However, mechanism...
The main aim of this thesis was to characterize mammalian chitotriosidase in terms of its function i...
Chitinases are enzymes that cleave chitin, a component of the exoskeleton of many organisms includin...
Pulmonary mycoses are often associated with type-2 helper T (Th2) cell responses. However, mechanism...
(A) Flow cytometric analysis of chitin particle size. The yellow peak indicates chitin particles. Gr...
Chitotriosidase secreted by activated human macrophages has been implicated in the defence against c...
Chitotriosidase (CHIT1) belongs to 18 glycosyl-hydrolase family, an ancient gene family that is wide...
Chitotriosidase (Chit1) is an enzyme associated with various diseases, including Gaucher disease, ch...
Allergic and parasitic helminth immunity is characterized by infiltration of tissues with IL-4- and ...
Background: Chitinolytic enzymes play important roles in the pathophysiology of allergic airway resp...
Pulmonary mycoses are often associated with type-2 helper T (Th2) cell responses. Howev-er, mechanis...
<p>(<b>A</b>) Cda2-MHCII tetramer identifies <i>C. neoformans</i>-specific helper T (Th) cells from ...
<p><b>1</b>) Chitotriosidase is released by the host and degrades fungal chitin to generate small ch...
Contains fulltext : 172746.pdf (publisher's version ) (Open Access)Chitotriosidase...
<p>(A-C) The BALB/c mice were intraperitoneally injected for 3 times at 7-day intervals with in-vitr...
Pulmonary mycoses are often associated with type-2 helper T (Th2) cell responses. However, mechanism...
The main aim of this thesis was to characterize mammalian chitotriosidase in terms of its function i...
Chitinases are enzymes that cleave chitin, a component of the exoskeleton of many organisms includin...
Pulmonary mycoses are often associated with type-2 helper T (Th2) cell responses. However, mechanism...
(A) Flow cytometric analysis of chitin particle size. The yellow peak indicates chitin particles. Gr...
Chitotriosidase secreted by activated human macrophages has been implicated in the defence against c...
Chitotriosidase (CHIT1) belongs to 18 glycosyl-hydrolase family, an ancient gene family that is wide...
Chitotriosidase (Chit1) is an enzyme associated with various diseases, including Gaucher disease, ch...
Allergic and parasitic helminth immunity is characterized by infiltration of tissues with IL-4- and ...
Background: Chitinolytic enzymes play important roles in the pathophysiology of allergic airway resp...
Pulmonary mycoses are often associated with type-2 helper T (Th2) cell responses. Howev-er, mechanis...
<p>(<b>A</b>) Cda2-MHCII tetramer identifies <i>C. neoformans</i>-specific helper T (Th) cells from ...